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人工周期冻融胚胎移植妊娠结局影响因素分析

龚梦 明蕾 李春燕 项燕

临床误诊误治Issue(6):93-96,4.
临床误诊误治Issue(6):93-96,4.DOI:10.3969/j.issn.1002-3429.2015.06.035

人工周期冻融胚胎移植妊娠结局影响因素分析

Analysis of Factors Influencing the Results of Frozen Embryo Transfer (FET) Treated with Hormone Replacement

龚梦 1明蕾 1李春燕 1项燕1

作者信息

  • 1. 430000 武汉,武汉大学人民医院生殖中心
  • 折叠

摘要

Abstract

Objective To explore the influencing factors of the pregnancy outcome of the frozen embryo transfer in ar-tificial cycles. Methods A retrospective analysis was performed for clinical data of 930 cases undergoing frozen embryo trans-fer treatment during Jan. 2011 and Dec. 2014. All patients accepted hormone replacement therapy. Endometrial thickness was monitored by transvaginal ultrasound. Estrogen ( E2 ) and progesterone ( P) level as well as E2/P ratio were recorded. Infertil-ity factors, time, age, ovulation induction regimen, insemination, endometrial thickness, E2 level, P level and E2/P ratio and their relation with the clinical pregnancy outcomes were analyzed. In addition, the multivariate Logistic Regression model was used to investigate the related factors affecting pregnancy outcome FET. Results Infertility time, age, endometrial thickness, P level, E2/P ratio and good quality embryo had a relationship with clinical pregnancy outcomes(P<0. 05,P<0. 01). Multi-variate logistic regression analysis showed that age, endometrial thickness and E2/P ratio could affect clinical pregnancy out-comes(P<0. 05,P<0. 01). Conclusion Regulating endometrial thickness, E2/ P ratio factors can improve clinical preg-nancy rate for patients undergoing FET in artificial cycle. Screening patients of suitable age is also an important means to im-prove the pregnancy rate.

关键词

人工周期/冻融胚胎移植/影响因素/临床妊娠率

Key words

Artificial cycle/Frozen embryo transfer/Influencing factor/Clinical pregnancy rate

分类

医药卫生

引用本文复制引用

龚梦,明蕾,李春燕,项燕..人工周期冻融胚胎移植妊娠结局影响因素分析[J].临床误诊误治,2015,(6):93-96,4.

临床误诊误治

OACSTPCD

1002-3429

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