摘要
Abstract
Objective To identify the risk factors of extrapulmonary manifestations in children with mycoplasma pneumoniae pneumonia ( MPP) , in order to reduce or prevent its occurrence through early intervention. Methods The clini-cal data of 558 hospitalized children with MPP from January 2011 to October 2014 were retrospectively reviewed. Based on the findings of extrapulmonary manifestations, the subjects were divided into 2 groups: the extrapulmonary manifestation group (235 cases) and non-extrapulmonary manifestation group (323 cases). The clinical data included gender, age, fever, hyper-pyrexia, rales, white blood cell count(WBC), C reaction protein(CRP), the manifestation of pneumonia on X-ray, the course of disease before admission, the initial time of macrolide antibiotics usage and so on. Single factor analysis and Logistic regression analysis were made in 2 groups. Results In up to 42. 11% of cases, a wide variety of extrapulmonary manifesta-tions occurred, which involved multiple body systems. The most 2 involved systems were urinary system and circulatory sys-tem, accounting for 15. 41% and 7. 35% respectively. Strong univariate associations suggested that some factors increase the risks of the occurrence of extrapulmonary manifestations of MPP: lobar/segmental MPP, the course of disease before admis-sion, WBC, CRP, the initial time of macrolide antibiotics usage. With multiple Logistic regression, independent risk factors of the occurrence of extrapulmonary manifestations of MPP were lobar or segmental MPP (OR=3. 660), the course of disease before admission (OR=1. 278), WBC (OR=1. 143), CRP (OR=0. 977) and the initial time of macrolide antibiotics us-age (OR=0. 652). Conclusion The extrapulmonary manifestations of MPP are not rare involving multiple body systems. Lobar or segmental MPP and the course of disease before admission are the two most important risk factors of inducing the oc-currence of extrapulmonary manifestations of MPP.关键词
肺炎,支原体/儿童/肺外表现/危险因素Key words
Pneumonia, mycoplasma/Child/Extrapulmonary manifestation/Risk factor分类
医药卫生
