华瑞芳 1舒峤 1刘勇 1曾小兵 1姬丽 1谢宝强 1廖金1
作者信息
- 1. 江西赣州市立医院内分秘科,江西 赣州 341000
- 折叠
摘要
Abstract
Objective To observe the curative ef ect of liraglutide treatmentseeking obese type 2 diabetes mel itus patients with cardiac insuf iciency.Methods 60 cases of obese type 2 diabetic patients in our hospital in 2013 January ~2014 June in our hospital, were randomly divided into observation group and control group. The observation group based on the original hypoglycemic drugs with liraglutide treatment, the control group using the original treatment of hypoglycemic drugs. Comparison of two methods in the treatment of patients before and after treatment,fasting blood glucose, 2H postprandial blood glucose, 2H postprandialinsulin and C peptide, glycosylated hemoglobin, blood pressure, weight,blood lipid. Results After the treatment, the observation group and the control group were FBG, 2hBG, BMI, HbAlc etc. have improved significantly, there are obvious dif erences and compared with those before the treatment, but the observation group and the control grouphad no significant dif erence between the two groups, P>0.05. In BMI,systolic pressure, men and women, waist and hip circumference, the treatment ef ect of the observation group was bet er than the control group, compared the dif erences, P< 0.05. After treatment, the observation group and the control group of patients with left ventricularejection fraction were lower than before treatment significantly improved,but the patients in the observation group is bet er than that of the control group patients, the two groups had dif erence,P<0.05, there was statistical significance. Conclusion With liraglutide treatment based onhypoglycemic drugs on the original, reducing the weight and blood pressure and blood lipid of patients, improved the function of islet beta cel s, improve the heart function of patients, is a new treatment option forpatients with type 2 diabetes mel itus heart dysfunction.关键词
利拉鲁肽/2型糖尿病肥胖患者/疗效观察Key words
Liraglutide/Type 2 diabetic patients with obesity/Curative ef ect observation