摘要
Abstract
Objective To study the ef ects of dexmedetomidine used in gastrointestinal operation analgesia ef ect on cognitive function of patients and nursing intervention measures analysis. Methods From 2013 August~2014 year in June,100 patients in our hospital scheduled for laparoscopic gastrointestinal operation, were randomly divided into observation group and control group, each group had 50 cases. Before anesthesia induction, 20 min observation group intravenous dexmedetomidine 1 μ g /kg, a maintenance dose of 0.1 μ g / (kg ·h) to 30 min before the end of operation. The control group with normal saline instead of dexmedetomidine and other conditions are the same. The control group was given conventional nursing, the treatment group on the basis of nursing intervention. Detection of plasma cortisol concentration in patients were started before administration, 1 h after operation and after operation;1 d before operation, 1 d after operation and 7d patients with the MMSE score, and calculate the rate of cognitive dysfunction after operation. Results Compared with control group, the observation group the incidence rate of postoperative cognitive dysfunction ( < 0.05) low. Cortisol concentration decreased significantly after induction of anesthesia ( < 0.05). Conclusion Dexmedetomidine was able to prevent gastrointestinal surgery in patients with cognitive dysfunction after operation, worthy of clinical applicatio.关键词
右美托咪啶/胃肠手术/镇痛/认知功能/护理干预措施Key words
Dexmedetomidine/Gastrointestinal operation/Analgesia/Cognitive function/Nursing intervention
