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反相高效液相色谱法测定氢化可的松洗剂的含量

余鹏 吴磊明 刘丹

医学信息Issue(26):76-76,77,2.
医学信息Issue(26):76-76,77,2.

反相高效液相色谱法测定氢化可的松洗剂的含量

Determination of Hydrocortisone Lotion by RP-HPLC

余鹏 1吴磊明 1刘丹1

作者信息

  • 1. 广东省皮肤病医院,广东 广州 510095
  • 折叠

摘要

Abstract

Objective To detect hydrocortisone in compound Hydrocortisone Lotion.Methods Using RP-HPLC,The chromatographic column was AKZONOBEL Kromasil C18 (250 mmí4.6mm, 5μm), Acetonitrile-water (28:72) was used as solvents. Results The linear range of hydrocortisone was 0.08~0.12mg·ml-1 (r=0.99995);The average recovery was 100.8%,with RSD=0.50%.Conclusion The method was simple,fast and accurate for the quality control of compound Hydrocortisone Lotion.

关键词

高效液相色谱法/氢化可的松洗剂/氢化可的松/含量测定

Key words

High performance liquid chromatography/Hydrocortisone lotion/Hydrocortisone/Determination of content

引用本文复制引用

余鹏,吴磊明,刘丹..反相高效液相色谱法测定氢化可的松洗剂的含量[J].医学信息,2015,(26):76-76,77,2.

医学信息

1006-1959

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