摘要
Abstract
Objective To investigate tbe clinical efficacy of anisodamine combined witb zinc gluconate for treating infantile rotavirus en-teritis. Methods Totally 73 patients witb infantile rotavirus enteritis in tbe pediatric department of tbe bospital were randomly divided into tbe study group(36 cases) and tbe control group(37 cases). Tbe two groups were given tbe conventional tberapy. Tbe study group was assisted by anisodamine plus zinc gluconate. Results Tbe abdominal pain,diarrbea,nausea and vomiting,borborygmus and remission or recovery time of body temperature in tbe study group bad statistically significant differences compared witb tbe tbose in tbe control ( P < 0. 05);tbe TNF-α,IL-2 and IL-15 levels after treatment in tbe two groups were significantly decreased compared witb before treatment( P < 0. 05 ),moreover tbe detection levels of tbese indexes in tbe study group were lower tban tbose in tbe control group( P < 0. 05);tbe treatment effective rate in tbe study group was 97. 22%,wbicb was significantly bigber tban 81. 08% in tbe control group ( P < 0. 05 );tbe negative conversion rate of fecal rotavirus after 72 b treatment in tbe study group was 61. 11%,wbicb was significantly bigber tban 37. 84% in tbe control group( P < 0. 05);tbe treatment time in tbe study group was(3. 7 ± 1. 5)d,wbicb was significantly lower tban (5. 0 ± 1. 7)d( P < 0. 05). Conclusion Tbe conventional treatment assisted by anisodamine combined witb zinc gluconate bas significant effect for tbe treatment of infantile rotavirus enteritis.关键词
山莨菪碱/葡萄糖酸锌/轮状病毒性肠炎Key words
anisodamine/zinc gluconate/rotavirus enteritis分类
医药卫生
