中国现代医生Issue(13)：147-152,6.
鼻咽癌转移相关分子标志物的研究进展
Research progress of molecular marker in metastasis of nasopharyngeal carcinoma
詹德超 1余忠华2
作者信息
- 1. 广东医学院，广东湛江 524000
- 2. 广东医学院附属医院肿瘤中心，广东湛江 524000
- 折叠
摘要
Abstract
Nasopharyngeal carcinoma is a malignant neoplasm which arises from the mucosal epithelium cells of the nasopharynx,it is also one of the common malignant tumors in southern China. Most nasopharyngeal carcinomas are poorly differentiated carcinomas. Nasopharyngeal carcinomas are high degree of malignancy,which prone to distant metastasis.The invasion and metastasis of neoplasm are associated with the perverted movement of cells,which is a dy-namic process of biologic behavior interactions among adhesion,degradation and angiogenesis in cancer cells. Howev-er,the molecular mechanisms underlying NPC invasion and metastasis have not fully elucidated. With the development of Modem molecular biology,more and more new molecular markers in NPC,such as biomarkers have been gotten to know the related molecules expression and molecular regulation, which play important roles in screening tumor mark-ers with more high sensitivity and specificity,achieving early diagnosis ,predicting treatment prognoses and providing new therapeutic strategies to make it more pertinent in anti-tumor therapy. This study is aimed to review the research progress of molecular marker in metastasis of nasopharyngeal carcinoma.关键词
鼻咽癌/转移/分子标志物Key words
Nasopharyngeal carcinoma/Metastasis/Molecular marker分类
医药卫生引用本文复制引用
詹德超,余忠华..鼻咽癌转移相关分子标志物的研究进展[J].中国现代医生,2015,(13):147-152,6.
