北京生物医学工程Issue(5)：454-457,4.DOI:10.3969/j.issn.1002-3208.2015.05.03
基于功能连接算法的斜视性弱视儿童静息态功能磁共振成像的研究
Research on resting state fMRI of strabismus amblyopia children based on functional connectivity algorithms
摘要
Abstract
Objective This paper studied the changes of strabismus amblyopia children’ s brain regions and functional connectivity, and revealed the correlation between the occurrence of strabismus amblyopia and changes in brain function� Methods Resting state fMRI of 22 strabismus amblyopia children and 10 healthy children were collected, and the connection coefficients of the whole brain and ROI functional areas were calculated by DPARSF software� Functional connectivity factors between and within groups were analyzed by t test� Results Brain functional connectivity of patients with strabismus amblyopia was lower than normal children’ s, mainly in occipital lobe, temporal lobe, posterior cerbellar lobe, parietal lobe, frontal lobe and cingulate gyrus� Conclusions Resting state connectivity algorithm of fMRI may reflect the changes of visual cortex and the changes of neural activities in multiple brain regions of strabismus amblyopia children.关键词
功能磁共振成像/功能连接算法/斜视性弱视Key words
functional magnetic resonance imaging/functional connectivity algorithm/strabismus amblyopia分类
医药卫生引用本文复制引用
周震,景斌,王洪,夏翃..基于功能连接算法的斜视性弱视儿童静息态功能磁共振成像的研究[J].北京生物医学工程,2015,(5):454-457,4.基金项目
首都卫生发展科研专项（2011－2015－05）资助 （）
