吉林大学学报(医学版)Issue(6):1215-1223,9.DOI:10.13481/j.1671-587x.20150623
完全腹腔镜与腹腔镜辅助远端胃癌根治术疗效比较的 Meta 分析
Totally laparoscopic distal gastrectomy and laparoscopically assisted distal gastrectomy:A Meta-analysis on efficacy comparison
摘要
Abstract
Objective To explore the effectiveness and safety of totally laparoscopic distal gastrectomy (TLDG)and laparoscopically assisted distal gastrectomy (LADG)for gastric cancer.Methods The comparative studies of TLDG and LADG published between 2008 and 2014 were searched from PubMed,EMBASE,Chinese Biomedical Literature Database (CBM),China National Knowledge Infrastructure (CNKI). After screening for inclusion, data extraction,and quality assessment,RevMan 5.3 software was used for Meta-analysis.Results Ten studies of 2 212 patients were included in the Meta-analysis,among whom 930 cases underwent TLDG and 1 282 cases underwent LADG.The results of Meta-analysis indicated that compared with LADG,TLDG had the advantages of less blood loss (WMD= - 20.70,95%CI:- 30.81 - - 10.59,P <0.01),less usage of analgesic (WMD=-0.38,95%CI:-0.74 - -0.02,P =0.04),more retrieved lymph nodes (WMD= 2.98,95%CI:0.71 -5.26,P =0.01).However,the Meta-analysis showed no statistically significant differences in the operation time, postoperative time-to-first flatus and oral intake,postoperative hospital stay,length of proximal resection margin, C reaction protein (CRP)level at postoperative day 1,incidence of overall complications and anastomosis-related complications.Conclusion TLDG is safe and effective with less blood loss, less pain than those of LADG. Moreover,it has comparable results to conventional LADG,with no increase of postoperative complications.关键词
完全腹腔镜远端胃癌根治术/腹腔镜辅助远端胃癌根治术/Meta 分析Key words
totally laparoscopic distal gastrectomy/laparoscopically assisted distal gastrectomy/Meta-analysis分类
医药卫生引用本文复制引用
陶有茂,吉国锋,马冲,肖玲..完全腹腔镜与腹腔镜辅助远端胃癌根治术疗效比较的 Meta 分析[J].吉林大学学报(医学版),2015,(6):1215-1223,9.基金项目
吉林省科技厅科技发展计划项目资助课题 ()