磁共振成像Issue(11)：843-847,5.DOI:10.3969/j.issn.1674-8034.2015.11.009
MR T2弛豫时间评估颈椎间盘退变的初步研究
Measurement of MR T2 relaxation time for assessing cervical intervertebral disc degeneration:preliminary study
摘要
Abstract
Abrtract Objective: To explore the value of T2 relaxation time (T2 value) measurement in detecting cervical intervertebral disc degeneration, and assessing age and disc level related intervertebral disc changes. Materials and Methods: Forty asymptomatic adult volunteers were examined at 1.5 T MR by T2-weighted sagittal imaging and T2-mapping. For all participants, Pfirrmann grading system and T2 value were used to evaluate the degenerative degree of the disks. Results:Signiifcant negative correlation were observed between Pifrrmann grades and T2 values of cervical intervertebral disc (r=-0.64, P<0.01). ANOVA (analysis of variance) among different Pfirrmann grades showed significant differences in T2 values (F=48.2,P<0.01), and signiifcant differences were seen between any 2 grades (P<0.05). The area under ROC curve of T2 value were 0.79, 0.81 and 0.78 (P<0.05) separately when gradeⅠvs.Ⅱ,Ⅱvs.Ⅲ, andⅢvs.Ⅳ. T2 values of 18—30 age group were higher than 31—40 age group participants (P<0.05). Signiifcant differences among different disc level were observed in 18—30 age group (P<0.05). However, in 31—40 age group, no significant differences of disc level were demonstrated (P>0.05). Conclusions:T2 relaxation time measurement is a quantitative-parameter for assessing cervical intervertebral disc degeneration and age and disc level related disc changes, and shall be used as a complementary sequence in detecting cervical disc degeneration for its certain clinical value.关键词
椎间盘退化/颈椎病/磁共振成像Key words
Intervertebral disc degeneration/Cervical spondylosis/Magnetic resonance imaging分类
医药卫生引用本文复制引用
黄耀渠,赵晓梅,伍琼惠,秦红卫..MR T2弛豫时间评估颈椎间盘退变的初步研究[J].磁共振成像,2015,(11):843-847,5.基金项目
广东省医学科研基金课题(编号A2013680)；佛山市科技局医学攻关课题(编号201308015) （编号A2013680）
