重庆医学Issue(21)：2458-2460,3.DOI:10.3969/j.issn.1671-8348.2013.21.006
35例重型颅脑损伤患者合并颅内感染的临床分析
Clinical analysis of 35 cases of craniocerebral injury patients with intracranial infection *
摘要
Abstract
Objective To investigate the characteristics of pathogenic bacteria/the drug resistance/the correlated risk fators/the prophylaxis control strategy of the severe craniocerebral injury patients combined with intracranial infection .Methods The clinical data of 35 craniocerebral injury patients with intracranial infection were retrospectively analyzed .Results 35 patients′cerebrospinal fluid were separated and 54 pathogenic bacterium had been cultured ,including G+ bacterium(61 .11% ) ,the G - bacteria(33 .33% ) , fungi(5 .56% ) .The pathogenic bacteria showed a higher resistance .The single factor analysis found that the wound itself exists in-fection factors ,the postoperative drainage of incision ,liquorrhoea ,with other basic diseases ,surgery lasted for a long time (>4 h) reoperative ,surgery is placed foreign body is severe craniocerebral trauma combined with intracranial infection were the main rele-vant factors .The total effective rate was 62 .86% ,and the mortality was 11 .43% by the positive therapy .Conclusion G+ bacteria were the main pathogenic bacterium in the severe craniocerebral injury patients combined with intracranial infection .The iatrogenic factors leaded to the increase of the proportion of intracranial infection and the resistance increased year after year .The clinical in-travenous antibiotics combined intrathecal injections were beneficial to control intracranial infection ,shorten the course of treatment and enhance the curative effect .关键词
重型颅脑损伤/颅内感染/病原菌/耐药性/危险因素Key words
severe craniocerebral injury/intracranial infection/pathogenic bacteria/drug resistance/risk factors引用本文复制引用
肖虹,程茗,黄警锐,胡唏,许毅,刘科..35例重型颅脑损伤患者合并颅内感染的临床分析[J].重庆医学,2013,(21):2458-2460,3.基金项目
重庆市卫生局医疗特色专科资助项目［渝卫科教（2010）52号］。 （）
