重庆医学Issue(28)：3938-3940,3.DOI:10.3969/j.issn.1671-8348.2015.28.014
OSA HS 患者不同程度氧减指数与血脂、肾功能相关性研究
Correlation between oxygen reduction index with blood lipid and renal function in OSAHS patients
摘要
Abstract
Objective To explore the correlation between oxygen reduction index(ODI) with blood lipid and renal function in patients with obstructive sleep apnea hypopnea syndrome(OSAHS) .Methods Selected 208 patients by polysomnography (PSG) and diagnosed as OSAHS ,divided into four groups according to ODI(ODI ≤ 7 ,7 < ODI ≤ 18 ,18 < ODI ≤ 38 and ODI > 38) .Four groups were compared in total cholesterol (TC) ,triglyceride (TG) ,high‐density lipoprotein cholesterol (HDL‐C) ,low density lipo‐protein cholesterol (LDL‐C) ,apolipoprotein A1 (ApoA1) ,apolipoprotein B (ApoB) ,urea ,creatinine ,uric acid and other differ‐ences ,analysis the correlation between ODI with blood lipid and renal function .Results There were significant different in TC ,TG , HDL‐C ,LDL‐C ,ApoB ,urea ,creatinine ,uric acid in four groups with different degree of ODI (P< 0 .05) ;ODI were positively relat‐ed to TC ,TG ,LDL‐C ,ApoB ,urea ,creatinine ,uric acid levels ,and negatively related to the level of HDL‐C .Conclusion Abnormity of blood lipid metabolic and changes in renal function are associated with the increase of ODI in patients with OSAHS .关键词
睡眠呼吸暂停低通气综合征/氧减指数/夜间间歇性低氧Key words
obstructive sleep apnea hypopnea syndrome/oxygen reduction index/nocturnal intermittent hypoxia分类
医药卫生引用本文复制引用
叶圆圆,蒋晓江,高东,李训军,刘雅贞,朗莹,林玲,杨信举..OSA HS 患者不同程度氧减指数与血脂、肾功能相关性研究[J].重庆医学,2015,(28):3938-3940,3.基金项目
军队保健专项面上项目（12BJZ51）。 （）
