重庆医学Issue(30)：4224-4226,3.DOI:10.3969/j.issn.1671-8348.2015.30.017
原发性醛固酮增多症筛查诊断影响因素的分析
Analysis of the influencing factors for screening primary aldosteronism
许红峰 1朱理敏1
作者信息
- 1. 上海交通大学医学院附属瑞金医院高血压科，上海200025
- 折叠
摘要
Abstract
Objective To confirm the most effectively screening conditions by comparing the ARR values of different posi‐tions after saline load test .Methods After exclusion the other secondary hypertension ,the completion of saline dressing test ,84 ca‐ses diagnosed hypertensive patients under saline load test results were divided into primary aldosteronism group (pH ,52 cases) and primary hypertension group (32 cases) .Analyzed plasma aldosterone (PAC) ,renin (PRA) values of upright and decumbent body positions ,their ARR values were calculated and the urine aldosterone was tested .Results Those whose upright position ARR rati‐os higher than 240(pg/mL)/(ng · mL -1 · h-1 ) were accounted for 80 .77% (42/52) and 43 .75% (14/32) ,respectively in the both PA group and PH group;Those whose upright position ARR ratios higher than 240(pg/mL)/(ng · mL -1 · h-1 ) and decumbent position PAC higher than 150 pg/mL were accounted for 65 .39% (34/52) and 3 .13% (1/32) ,respectively in the both PA group and ph group;The specificity of this method for PA was 96 .88% .Those whose upright position ARR ratios higher than 240(pg/mL)/(ng · mL -1 · h-1 ) and decumbent position PAC higher than 150 pg/mL and urine aldosterone higher than 10 μg/24 h ,The specificity of this method for PA was 100 .00% .Conclusion It is an effective screening method for primary aldosteronism when ARR values of upright position higher than 240(pg/mL)/(ng · mL -1 · h-1 ) ,PAC of decumbent position higher than 150 pg/mL and urine aldosterone higher than 10 μg/24 h .关键词
原发性醛固酮增多症/血浆醛固酮/肾素比值/尿醛固酮/盐水试验Key words
primary aldosteronism/aldosterone-to-renin ratio/urine aldosterone/saline load test分类
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许红峰,朱理敏..原发性醛固酮增多症筛查诊断影响因素的分析[J].重庆医学,2015,(30):4224-4226,3.
