动物营养学报2015，Vol.27Issue(11)：3338-3344,7.DOI:10.3969/j.issn.1006-267x.2015.11.004
钠离子依赖性中性氨基酸转运载体2特性、表达调控及功能
Sodium Dependent Neutral Amino Acid Transporter 2:Characteristics, Expression Regulation and Function
摘要
Abstract
Sodium-dependent neutral amino acid transporter 2 ( SNAT2 ) , which belongs to transport system A,is the main transporter of nitrogen in vivo. SNAT2 is well known as typical amino acid transceptor founded in recent years, which plays a dual role of amino acid transporter and receptor through regulating the concentra-tion of intracellular amino acids, thereby regulating the downstream signal of intracellular amino acid receptors. Because of its unique features, SNAT2 has become an attractive topic in nutritional induction of amino acids in recent years. In the present review, the new research progresses on the molecular characteristics, biological properties, expression regulation and amino acids sensing signaling of SNAT2 were summarized.关键词
钠离子依赖性中性氨基酸转运载体/分子特性/生物学特性/表达调控/哺乳动物雷帕霉素靶蛋白信号通路Key words
sodium-dependent neutral amino acid transporter 2/molecular characteristic/expression regula-tion/mTOR signaling pathway分类
农业科技引用本文复制引用
李光燃,谭碧娥,管桂萍,印遇龙..钠离子依赖性中性氨基酸转运载体2特性、表达调控及功能[J].动物营养学报,2015,27(11):3338-3344,7.基金项目
国家自然科学基金(31372326,31330075,31301989) （31372326,31330075,31301989）
国家重点基础研究发展计划(2013CB127302) （2013CB127302）
