中国耳鼻咽喉头颈外科Issue(10)：523-525,3.DOI:10.16066/j.1672-7002.2015.10.010
白细胞介素17与血管内皮生长因子在鼻息肉组织中的表达及相关性分析
Interleukin 17 and vascular endothelial growth factor expression and correlation analysis in nasal polyp tissues
刘楠 1刘达 2刘领波 3李红英 3张亚宁 3赵勇 3郑伟红 3刘屹3
作者信息
- 1. 承德医学院研究生学院，河北 承德067000
- 2. 第四军医大学航空航天系，陕西 西安710032
- 3. 保定市第一医院耳鼻咽喉头颈外科，河北 保定071000
- 折叠
摘要
Abstract
[ABSTRACT]OBJECTIVETo explore the occurrence and development of nasal polyps by studying the interleukin 17 and vascular endothelial growth factor expression level in nasal polyp tissues.METHODSNasal polyps in 30 patients with chronic sinusitis (with polyps), ethmoid sinus mucosa in 30 patients with chronic sinusitis (without polyps), inferior turbinate mucosa in 10 patients with nasal septum deviation were collected intraoperatively. IL-17 and VEGF expression were detected using immunohistochemistry SP testing, and correlation between them was analysed. RESULTS1. The expression of IL-17 and VEGF in nasal polyps group is significantly higher than that of the other two groups.There was significant difference between each two groups statistically (P<0.01). 2. The expression of IL-17 was positively correlated with VEGF expression in nasal polyps.CONCLUSION1. The expression of IL-17 and VEGF increased in nasal polyp tissues. 2. The expression of IL-17 and VEGFwas positively correlated in nasal polyps , and both of them take part in the occurrence and development of nasal polyps.关键词
白细胞介素17/血管内皮生长因子类/鼻息肉/免疫组织化学Key words
Interleukin-17/Vascular Endothelial Growth Factors/Nasal Polyps/Immunohistochemistry引用本文复制引用
刘楠,刘达,刘领波,李红英,张亚宁,赵勇,郑伟红,刘屹..白细胞介素17与血管内皮生长因子在鼻息肉组织中的表达及相关性分析[J].中国耳鼻咽喉头颈外科,2015,(10):523-525,3.
