国际医药卫生导报2015，Vol.21Issue(19)：2828-2830,3.DOI:10.3760/cma.j.issn.1007-1245.2015.19.006
不同孕期孕妇血清25-羟维生素D水平的研究
Serum 25-hydroxy vitamin D levels in pregnant women in different periods
钟田花 1刘紫菱 1王海燕 1赖科峰 1穆小萍1
作者信息
- 1. 511400 广州,广东省妇幼保健院检验科
- 折叠
摘要
Abstract
Objective To investigate the serum 25-hydroxy vitamin D [25-(OH)D] levels in pregnant women in different periods.Methods 1254 pregnant women were enrolled into this study during their visit at Guangdong Women and Children Hospital between December, 2014 and May, 2015.The subjects were divided into three groups according to pregnant periods: first trimester group (<14 weeks), second trimester group (14-28 weeks), and third trimester group (>28 weeks).Serum 25-(OH)D levels were measured by ELISA.The differences of 25-(OH)D levels were compared between these three groups.Results (1)The median of serum 25-(OH)D was 32.00 (16.57-53.57) nmol/L in first trimester group, 34.00 (17.11-64.52) nmol/L in second trimester group, and 33.30 (17.10-70.63) nmol/L in third trimester group,with statistical differences between these three groups showed by kruskal-wallis test (Z=6.060, P<0.05).(2)The rates of 25-(OH)D deficiency and insufficiency were 17.75％ (30/169) and 81.66％ (138/169) in first trimester group, 12.29％ (118/960) and 85.94％ (825/960) in second trimester group, and 17.60％ (22/125) and 80.80％ (101/125) in third trimester group, respectively.There was a statistical difference in the distribution of serum 25-(OH)D levels between first and second trimester group (Z=2.162, P<0.05).Conclusions Vitamin D deficiency and insufficiency are common in women in different pregnant periods,especially in first trimester.关键词
孕妇/维生素D/孕期Key words
Pregnant women/25-hydroxy Vitamin D/Pregnant period引用本文复制引用
钟田花,刘紫菱,王海燕,赖科峰,穆小萍..不同孕期孕妇血清25-羟维生素D水平的研究[J].国际医药卫生导报,2015,21(19):2828-2830,3.
