摘要
Abstract
Objective To explore the clinical efficacy of enalapril in the combination with atorvastatin calcium for early diabetic nephropathy.Methods 126 patients with early diabetic nephropathy were randomly divided into a control group, an enalapril group, and a combination group.The blood glucose, blood lipid, and renal indexes were compared between these three groups before and after the treatment.Results After the treatment, there were no statistical differences in FBG and HbA1c between these three groups (P>0.05).TC, TG, Cys-C, Scr, U-mA1b, and beta 2-MG were lower and HDL-C was higher after than before the treatment in the enalapfil group and the combination group, with statistical differences (P<0.05).After the treatment, TC[(4.03±0.37) mmol/L], TG[(1.33±0.25) mmol/L], Cys-C[(1.63±0.16) mg/L], Scr[(75.33±12.87) μmol/L], U-mA1b[(150.06±13.88) mg/L], and β2-MG[(2.57±0.93)mg/ml] were lower and HDL-C[(1.68±0.63) mmol/L] was higher in the combination group than in the enalapril group than the control group, with statistical differences (P<0.05).Conclusions Enalapril in the combination with atorvastatin calcium for early diabetic nephropathy can obviously inhibit lipid metabolism disorder, protect kidney, and delay renal damage development process.关键词
早期糖尿病肾病/依那普利/阿托伐他汀钙Key words
Early diabetic nephropathy/Enalapril/Atorvastatin calcium
