摘要
Abstract
Objective To investigate the clinical auxiliary effect of dexmedetomidine in spinal anesthesia.Methods 50 patients admitted in our hospital from January 2013 to April 2015 for lower limb surgery with subarachnoid anesthesia or epidural anesthesia were selected for prospective study, and randomly divided into two groups with 25 cases in each group.After anesthetized successfully, patients in control group were given intravenous pumping of normal saline, while patients in experimental group were given intravenous pumping of dexmedetomidine.AAI, Ramsay sedation score and adverse reactions of two groups at different stages were compared.Results AAI of experimental group at T1, T4 were significantly lower than those of control group (P＜0.01), there were no statistically significant differences in AAI at T0, T2, T3 between two groups (P＞0.05).Ramsay sedation score of experimental group at T1, T2, T3, T4 were significantly higher than those of control group, with statistically significant differences between two groups (P＜0.01).The incidences of nausea, emesis,dysphoria, respiratory depression, bradycardia of experimental group were significantly lower than those of control group, with statistically significant differences between two groups (P＜0.05).Conclusion Dexmedetomidine has significant clinical auxiliary effect in spinal anesthesia, with stable sedation effect and good safety, therefore it is of referentiability.关键词
右美托咪啶/椎管内麻醉/AAI值/Ramsay镇静评分/不良反应Key words
Dexmedetomidine/Spinal anesthesia/AAI/Ramsay sedation score/Adverse reaction
