卵巢癌早期诊断的血清肿瘤标记物研究进展OACSTPCD
Research Progress in Serum Tumor Markers of Early Diagnosis of Ovarian Cancer
卵巢癌是女性生殖系统中病死率最高的恶性肿瘤，由于缺乏早期有效的筛查手段，多数患者确诊时已为晚期，治愈率只有20%～30%，而早期患者的生存率较晚期患者高。因此，提高卵巢癌的早期诊断是改善患者生存质量的重要且有效的途径。目前临床上主要的筛查手段是经阴道超声检查联合血清肿瘤标记物的检测。除了糖类抗原125（CA125）广泛用于卵巢癌的诊断、检测和预后评估外，人附睾蛋白4（HE4）、骨桥蛋白（OPN）、间皮素（MSLN）和协同刺激分子B7-H4等生物学…查看全部>>
Ovarian cancer is the most leading cause of death in gynecologic malignancies. Since lack of early detection strategies, the majority of the patients are diagnosed at advanced stage disease, of which the cure rate is only 20%-30%. It has been observed that the survival rate of patients at early stages is higher than those diagnosed with advanced disease. Therefore, to improve the quality of patients′life, it is important and effective to get the early diagno…查看全部>>
岳娟;刘菲;李艳红
710038 西安，第四军医大学唐都医院妇产科710038 西安，第四军医大学唐都医院妇产科710038 西安，第四军医大学唐都医院妇产科
卵巢肿瘤肿瘤标记,生物学CA-125抗原附睾分泌蛋白质类骨桥蛋白质
Ovarian neoplasmsTumor markers,biologicalCA-125 antigenEpididymal secretory proteinsOsteopontin
《国际妇产科学杂志》 2015 (5)
560-563,4
卫生部医药卫生技术发展研究中心课题（W2013FZ13）
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