摘要
Abstract
Objective To evaluate the sensitivity and specificity of pulse oximetry ( POX) with clinical examination in diagnosis of neonatal congenital heart disease (CHD).Methods All of the neonates aged 3-28 days old born during May 1, 2014 and February 28, 2015 in neonatal department were chosen for screening, and the cases diagnosed with CHD already or requiring monitoring by instruments were excluded.Cases with positive clinical assessment accepted echocardiography, and all cases were detected by POX.Cases with results of both negative clinical assessment and POX were followed up and gave feedback at 42-day.Results Of enrolled 796 cases, 57 cases were diagnosed with CHD, including 4 cases of critical CHD.The sensitivity of POX, single clinical examination, and POX combing clinical examination was 19.3%, 91.22% and 96.5%, respectively, and the specificity of them was 99.46%, 93.64% and 93.5%, respectively.Among three methods, the specificity of POX was highest,and that of POX combining clinical examination was lower(χ2 =55.32, P<0.001).The sensitivity of POX combining clinical examination was highest (χ2 =1738.75, P <0.001).Conclusion Combining POX with clinical examination can improve the detection rate of CHD, especially critical CHD.关键词
脉搏血氧饱和度检测/体格检查/新生儿/先天性心脏病/复杂型Key words
pulse oximetry ( POX)/clinical examination/neonate/congenital heart disease ( CHD)/critical分类
医药卫生