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维生素 D缺乏性佝偻病与婴幼儿反复呼吸道感染的关系

李晓辉 熊光明

中国妇幼健康研究Issue(5):1064-1065,2.
中国妇幼健康研究Issue(5):1064-1065,2.DOI:10.3969/j.issn.1673-5293.2015.05.056

维生素 D缺乏性佝偻病与婴幼儿反复呼吸道感染的关系

Relationship between vitamin D deficiency rickets and infant recurrent respiratory tract infection

李晓辉 1熊光明2

作者信息

  • 1. 宁波大榭开发区医院儿内科,浙江宁波315800
  • 2. 宁波市北仑区人民医院儿科,浙江宁波315800
  • 折叠

摘要

Abstract

Objective To study the relationship between vitamin D deficiency rickets and recurrent respiratory tract infection in infants. Methods Totally 236 cases of recurrent respiratory tract infection were chosen in observation group, and 108 infants receiving physical examination were randomly selected in control group.The incidence of vitamin D deficiency rickets was observed in two groups, and serum 25 (OH)D3 and alkaline phosphatase (AKP) concentrations were compared between two groups.Results In the observation group rickets were found in 69 cases (29.2%) and vitamin D sub clinical state in 48 cases (20.3%), while in the control group there were 16 cases (14.8%) and 29 cases (27.4%), respectively.The incidence in two groups was significantly different (χ2 =11.22,P <0.05). Compared with the control group, serum 25 ( OH) D3 , AKP, IgG and IgA concentrations in the observation group were lower but AKP concentration was higher with significant difference (t value was 14.18, 8.74, 16.73, 1.67 and 4.11, respectively, all P<0.05). Conclusion Infants vitamin D deficiency rickets is closely related with recurrent respiratory tract infection.Preventive supplementation of vitamin D is an effective way to improve infant immune function and prevent recurrent respiratory tract infection.

关键词

维生素D缺乏性佝偻病/反复呼吸道感染/25羟基维生素D3/碱性磷酸酶

Key words

vitamin D deficiency rickets/recurrent respiratory tract infection/25-( OH) D3/alkaline phosphatase ( AKP)

分类

医药卫生

引用本文复制引用

李晓辉,熊光明..维生素 D缺乏性佝偻病与婴幼儿反复呼吸道感染的关系[J].中国妇幼健康研究,2015,(5):1064-1065,2.

中国妇幼健康研究

OACSTPCD

1673-5293

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