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维持性血液透析老年患者认知功能水平的调查研究

鄢建军 刘蔚 朱波 吴会军 孙新 刘娜利

医学分子生物学杂志Issue(5):281-285,5.
医学分子生物学杂志Issue(5):281-285,5.DOI:10.3870/j.issn.1672-8009.2015种.05N.008

维持性血液透析老年患者认知功能水平的调查研究

Cognitive Impairment and Its Risk Factors in Elder Patients with Ma-intenance Hemodialysis

鄢建军 1刘蔚 1朱波 1吴会军 1孙新 2刘娜利3

作者信息

  • 1. 华中科技大学同济医学院附属同济医院肾内科 武汉市,430030
  • 2. 华中科技大学同济医学院附属协和医院血液透析室 武汉市,430030
  • 3. 湖北咸宁市中心医院 咸宁同济医院 肾内科 湖北省咸宁市,437000
  • 折叠

摘要

Abstract

Objective To investigate the cognitive status of elder patients with maintenance hemodialysis ( MHD) and the risk factors of cognitive impairment in these patients in order to pro-vide clues for the management of chronic patients with MHD.Methods A total of 112 patients at age of 60 or older who received MHD were enrolled in this study.Cognitive performance was evalua-ted by Chinese Simple Mental State Examination Scale ( CMMSE) and Activity of Daily Living Scale ( ADL) .Clinical data, including gender, age, education level, dialysis duration, vascular ac-cess, primary diseases, and medical history, were recorded, and the last pre-dialysis hemoglobin and serum albumin measurements were obtained.Results The average CMMSE score was 24.9 ± 5.7.CMMSE score was less than 27 points in 75 cases and 37 cases scored more than 27 points.The cognitive impairment rate in this cohort was 67.0%.There was significant difference in sex, age, level of education, history of diabetes, self-care ability, and serum albumin level between cogni-tive impairment group and normal group ( P<0.05 ) .Conclusion Cognitive impairment is com-mon in elder MHD patients.The risk factors for cognitive impairment are age, level of education, diabetes, self-care ability and serum albumin levels.The patients with elder age, low education and self-care disability are more likely to develop cognitive impairment.

关键词

血液透析/老年人/认知功能/简易智能状态检查

Key words

hemodialysis/old people/cognitive function/mini-mental state examination

分类

医药卫生

引用本文复制引用

鄢建军,刘蔚,朱波,吴会军,孙新,刘娜利..维持性血液透析老年患者认知功能水平的调查研究[J].医学分子生物学杂志,2015,(5):281-285,5.

医学分子生物学杂志

OACSTPCD

1672-8009

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