国际口腔医学杂志Issue(1):55-58,63,5.DOI:10.7518/gjkq.2013.01.015
宏基因组学及其在口腔微生物研究领域中的应用
The research methods of metagenomic and the application of metagenomic study in the oral microbiota
摘要
Abstract
Metagenomics is the genomes of the total microbiota found in nature. Metagenome libraries were con-structed by directly extracting DNA from environmental samples, Such as soil, oceans, human gastrointestinal tract and mouth, etc., and transforming to surrogate host. The libraries were screened for novel bioactive compounds or genes. Therefore, Metagenomics can effectively detect oral microbial community structure, and also can enormously amplified the space of microbial resource utilization and enhanced the opportunity of obtain novel bioactive com-pounds. This review included the research progress of the methods of metagenomic and the application of metage-nomic study in the oral microbiota.关键词
宏基因组学/微生物群落/遗传物质/口腔Key words
metagenomics/microorganism structure/genetic material/oral分类
生物科学引用本文复制引用
陆剑,李宇红,杜民权..宏基因组学及其在口腔微生物研究领域中的应用[J].国际口腔医学杂志,2013,(1):55-58,63,5.基金项目
国家自然科学基金资助项目(81170954) (81170954)