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细胞自噬及其与口腔鳞状细胞癌间的相关性

邢雪 卢树静 金鑫 陈谦明 曾昕

国际口腔医学杂志Issue(1):155-159,5.
国际口腔医学杂志Issue(1):155-159,5.DOI:10.3969/j.issn.1673-5749.2013.01.000

细胞自噬及其与口腔鳞状细胞癌间的相关性

Cell autophagy and its correlation with oral squamous cell carcinoma

邢雪 1卢树静 1金鑫 1陈谦明 1曾昕1

作者信息

  • 1. 口腔疾病研究国家重点实验室,四川大学 成都 610041
  • 折叠

摘要

Abstract

Cell autophagy is one type of programmed cell death in eukaryotic cells. And it has been widely impli-cated in many physiological and pathological processes, including cancer. Cell autophagy is a bulk degradation system, which controls the clearance and re -use of intracellular constituents, and is important for the maintenance of an amino acid pool essential for survival. Recent studies show that cell autophagy is correlated closely to oral squamous cell carcinoma. This review summarizes classifications、functions、regulatory mechanisms and autophagy-related gene and protein. This review also concentrate on predisposing factors of cell autophagy and the correlation between cell au-tophagy and oral squamous cell carcinoma and other tumor.

关键词

细胞自噬/口腔鳞状细胞癌/肿瘤

Key words

cell autophagy/oral squamous cell carcinoma/tumor

分类

医药卫生

引用本文复制引用

邢雪,卢树静,金鑫,陈谦明,曾昕..细胞自噬及其与口腔鳞状细胞癌间的相关性[J].国际口腔医学杂志,2013,(1):155-159,5.

基金项目

国家自然科学基金资助项目(30930100,81072218,30-872872) (30930100,81072218,30-872872)

四川省青年科技基金资助项目(09ZQ026-037) (09ZQ026-037)

国际口腔医学杂志

OACSTPCD

1673-5749

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