国际口腔医学杂志Issue(2)：257-260,264,5.DOI:10.7518/gjkq.2013.02.033
上皮-间质转化诱导因子及其与口腔鳞状细胞癌间的相关性
Inducers of epithelial mesenchymal transformation and its correlation with oral squamous cell carci-noma
摘要
Abstract
Epithelial—mesenchymal transformation(EMT) can be viewed as the loss of original epithelium cell characteristic, such as loss of polarity, loss of epithelial markers, cytoskeletal reorganization, and transition to a spin-dle-shaped morphology concomitant with acquisition of mesenchymal markers(including α-smooth muscle actin) and an invasive phenotype. EMT plays an important role in the invasion and metastasis of cancer. This article reviews the important inducers of signaling pathways in EMT and highlights recent advances in the studies of signaling pathways in EMT in oral squamous cell carcinoma.关键词
上皮-间质转化/信号通路/口腔鳞状细胞癌Key words
epithelial-mesenchymal transformation/signaling pathway/oral squamous cell carcinoma分类
医药卫生引用本文复制引用
卢树静,邢雪,刘娜,陈谦明,曾昕..上皮-间质转化诱导因子及其与口腔鳞状细胞癌间的相关性[J].国际口腔医学杂志,2013,(2):257-260,264,5.基金项目
国家自然基金资助项目(30930100,81072218,3087-2872) （30930100,81072218,3087-2872）
四川省青年科学基金资助项目(09ZQ026-037) （09ZQ026-037）
