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甘草水煎剂对变异链球菌黏附影响的体外实验

黄萍 万呼春 田婷玉 何永红

国际口腔医学杂志Issue(3):285-287,3.
国际口腔医学杂志Issue(3):285-287,3.DOI:10.7518/gjkq.2013.03.002

甘草水煎剂对变异链球菌黏附影响的体外实验

Effects of licorice decoction on the adherence of Streptococcus mutans in vitro

黄萍 1万呼春 1田婷玉 1何永红1

作者信息

  • 1. 口腔疾病研究国家重点实验室,华西口腔医院特诊科,四川大学 成都 610041
  • 折叠

摘要

Abstract

Objective To determine the effects of licorice decoction on the adherence of Streptococcus mutans in vitro and the possible mechanisms. Methods Licorice decoction was from self-preparation. According to the licorice decoction’s mass concentration 25, 50 and 100 g·L-1, the experiment were divided into A, B and C groups. The group not containing decoction was set as negative control group. The experiment was performed in the glass tubes. Bacteria adhering tightly, loosely or not adhering to the glass were collected separately to determine bacteria’s adhesion rates. The quantity of water insoluble extracellular polysaccharides produced by bacteria was measured by anthrone method. Results Bacteria’s adhesion rates of A, B, C and negative control groups were 70.2%, 40.1%, 14.2% and 87.1% respectively. Water insoluble extracellular polysaccharides’s mass concentration of each group was 0.28, 0.25, 0.13, 0.30 g·L -1. Conclusion Licorice decoction has inhibitory potential against the adherence of Streptococcus mutans to smooth surface. The inhibition was dose-dependent, and may be relevant with the inhibition of synthesis of water insoluble extracellular polysaccharides.

关键词

甘草/变异链球菌/黏附

Key words

licorice/Streptococcus mutans/adherence

分类

医药卫生

引用本文复制引用

黄萍,万呼春,田婷玉,何永红..甘草水煎剂对变异链球菌黏附影响的体外实验[J].国际口腔医学杂志,2013,(3):285-287,3.

国际口腔医学杂志

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