国际口腔医学杂志Issue(3)：364-367,4.DOI:10.7518/gjkq.2013.03.023
高迁移率族蛋白N家族抗肿瘤活性的研究进展
Research progress on high mobility group N in anti-tumor activity
摘要
Abstract
High mobility group(HMG) protein is a non-histone protein that is widely present in eukaryotes chromatin. HMG wins its name because of its small molecular weight and rapid migration in polyacrylamide gel electrophoresis. DNA damage originated from both ultra violet light and ionizing irradiation. High mobility group N (HMGN) protein is an emerging factor that is important for chromatin alterations in response to DNA damage. DNA lesions threaten the integrity of the genome and are a major factor in cancer formation and progression. The role of HMGN in anti-tumor will be discussed.关键词
高迁移率族蛋白N家族/DNA损伤反应/抗肿瘤Key words
high mobility group N/DNA damage response/anti-tumor分类
生物科学引用本文复制引用
董小倩,冯云..高迁移率族蛋白N家族抗肿瘤活性的研究进展[J].国际口腔医学杂志,2013,(3):364-367,4.基金项目
眼基金项目演国家自然科学基金资助项目 （）
