国际医学放射学杂志Issue(3)：205-209,5.DOI:10.3874/j.issn.1674-1897.2013.03.L0301
正常成人外侧膝状体MR显示序列的初步研究
Identify normal anatomy of lateral geniculate nucleus with MRI:a preliminary study
吴永顺 1蒋伟 1叶瑞心 1钟镜联 1梁碧玲 1黄穗乔1
作者信息
- 1. 510120 广州，中山大学孙逸仙纪念医院放射科
- 折叠
摘要
Abstract
Objective To explore the normal morphology of the normal lateral geniculate nucleus (LGN) with different MRI sequences. To establish an anatomical reference for the fiber tracking, clinical diagnosis or research of optic pathway lesion of visual system. Methods There were ten healthy volunteers enrolled and each underwent axial T2-FLAIR and T1W-IR TSE, and axial and coronal PDW and T2 TSE. The signal-to-noise ratio (SNR) of LGN and contrast-to-noise ratio (CNR) of LGN to the surrounding tissue [optic radiation, posterior limb of the internal capsule (PLIC) and cerebrospinal fluid] were calculated. Image quality evaluation of the LGN on different sequences was made. The maximum height and the volume of bilateral LGN were measured. Results On PDW images, the LGN could be clearly shown in all cases. It often manifested as a small wedge-shaped or triangular area of high signal intensity relative to the surrounding white matter tracts. However, it was difficult to identify the LGN on other four sequences due to lower CNR between the LGN and the adjacent white matter tracts. The scores of LGN on PDW statistically differed with other three sequences (F=165.883,P<0.001);SNR (93.02±12.20), CNR to the PLIC (8.32±4.32) and CNR to the optic radiation (6.91±3.25) on PDW turbo spin-echo images were significantly higher than those on all other images (P<0.05). The mean heights and volumes of the normal adults were (4.51±0.29) mm and (95.62±3.41) mm3 of the right LGN, respectively; (4.48±0.32) mm and (97.47±2.70) mm3 of the left LGN respectively. There were no significant differences between right and left sides (t=-0.116, P=0.910; t=1.386, P=0.199). Conclusions (1)The PDW sequence can identify the anatomy of LGN clearly and can be used to measure the maximum height and the volume. (2)The PDW sequence can provide ideal anatomical reference for the studies of visual function, optic pathway lesions, and the fiber tracking of visual pathways.关键词
外侧膝状体/磁共振成像/双回波自旋序列/信噪比/对比噪声比/视放射Key words
Lateral geniculate nucleus/MRI/DUAL TSE/Signal-to-noise ratio/Contrast-to-noise ratio/Optic radiation引用本文复制引用
吴永顺,蒋伟,叶瑞心,钟镜联,梁碧玲,黄穗乔..正常成人外侧膝状体MR显示序列的初步研究[J].国际医学放射学杂志,2013,(3):205-209,5.
