临床与病理杂志Issue(10)：1773-1777,5.DOI:10.3978/j.issn.2095-6959.2015.10.014
儿童先天性肺气道畸形73例临床病理分析
Congenital pulmonary airway malformation of the lung in children：a clinicalpathological analysis of 73 cases
舒艳 1朱坤 1汤宏峰 1赵曼丽 1杨敏 1赵云 1刘蕾 1李俊平1
作者信息
- 1. 浙江大学医学院附属儿童医院病理科，杭州 310013
- 折叠
摘要
Abstract
Objective: To explore the clinical, imaging, pathological feature and prognosis of congenital pulmonary airway malformation (CPAM).Methods: Retrospect analysis the clinical pathologic features of 73 cases of CPAM and review related literatures.Results: Patients’ age ranges from 1 day to 15 years, with mean age 4.3 years old. CPAM has no sex predilection. Histologic examination showed that 49 cases were classiifed as Stocker type I, 22 cases as type II, 2 cases as type III. All were unilateral lesion and involvement on the letf side of the 29 cases, on the right side of 44 cases. Of the 73 cases studied, the associated malformations included cardiac anomalies(6 cases), arachnoid cyst (2 cases), invisible spinal biifda and thyroid dysplasia (1 case), brain development backwardness and hydrocephalus (1 case), wilm’s tumor (1 case). All of the 73 cases performed X-ray or CT examination: except mass-like change for 2 cases, the others showed single or multiple large air cystic lesions; honeycomb-like small cystic lesions, the cyst lack of lung marking. All cases were underwent lobectomy, Follow-up time ranges from 2~25 months, except 2 cases died of type III, the rest of 71 cases recovered well.Conclusion:CPAM is a relatively rare pulmonary lesion of congenital cystic adenomatoid malformation. Imaging analysis is a valuable tool to suggest CPAM, while deifnite diagnosis requires pathologic examination. Surgical excision, commonly lobectomy is recommended.关键词
肺气道畸形/儿童/肺叶切除术/预后Key words
pulmonary airway malformation/children/lobectomy/prognosis引用本文复制引用
舒艳,朱坤,汤宏峰,赵曼丽,杨敏,赵云,刘蕾,李俊平..儿童先天性肺气道畸形73例临床病理分析[J].临床与病理杂志,2015,(10):1773-1777,5.
