临床与病理杂志Issue(10)：1816-1820,5.DOI:10.3978/j.issn.2095-6959.2015.10.022
中医证型与2型糖尿病患者胰岛素抵抗及B细胞功能的关系
The corresponding relationship of insulin resistance, injury of isletβ-cell function and evolution of TCM syndromes in patients with T2DM
摘要
Abstract
Objective: Analyze the corresponding relationship of insulin resistance, injury of islet β-cell function and evolution of Traditional Chinese Medicine (TCM) syndromes in patients with type 2 diabetes mellitus (T2DM). Methods: We studied 98 cases of Endocrinology inpatients from the Suzhou Hospital of TCM for the diagnosis and treatment of diabetes, divided into Yin deifciency and heat syndrome, syndrome of phlegm-damp invading the spleen, Qi and Yin deifciency syndrome, and Yang and Yin deifciency syndrome. Analyzed the corresponding relationship of insulin resistance, injury of islet β-cell function and evolution of TCM syndromes in patients with T2DM.Results: Four types of syndrome and Fins, CPS have no significance (P>0.05). Fins with syndrome of phlegm-damp invading the spleen was highest, and then Qi and Yin deficiency syndrome, Yang and Yin deifciency syndrome was lowest. CPS with Qi and Yin deifciency syndrome was highest, and then Yin deifciency and heat syndrome, Yang and Yin deficiency syndrome was lowest. Four types of syndrome and HOMA-IR, ISI, HMOA-β have no significance (P>0.05). HOMA-IR with syndrome of phlegm-damp invading the spleen was highest, and according to Qi and Yin deifciency syndrome, Yin deifciency and heat syndrome, Yang and Yin deifciency syndrome gradually increased. According to Yin deifciency and heat syndrome, syndrome of phlegm-damp invading the spleen, Qi and Yin deifciency syndrome, and Yang and Yin deifciency syndrome, ISI gradually decreased. HOMA-β with syndrome of phlegm-damp invading the spleen was highest, and according to Yin deficiency and heat syndrome, Qi and Yin deficiency syndrome, Yang and Yin deficiency syndrome gradually decreased. Four types of syndrome and HbA1c, FPG, 2hPG have no signiifcance (P>0.05).Conclusion: 1) Yin deficiency and heat syndrome, syndrome of phlegm-damp invading the spleen were mainly to IR. Qi and Yin deficiency syndrome, Yang and Yin deficiency syndrome were mainly to function of βcells reduced. 2) TCM syndromes were mainly to syndrome of phlegm-damp invading the spleen throughout the disease always. Point out: Damp Retention may be more important diabetes pathogenesis in Suzhou.关键词
中医证型/2型糖尿病/胰岛素抵抗/B细胞功能Key words
TCM syndromes/type 2 Diabetes/insulin resistance/the function of pancreatic islet引用本文复制引用
黄菲,王纯庠..中医证型与2型糖尿病患者胰岛素抵抗及B细胞功能的关系[J].临床与病理杂志,2015,(10):1816-1820,5.基金项目
苏州市科技局课题(SYS201260)。@@@@This work was supported by Suzhou Science and Technology Bureau Project Foundation (SYS201260), P. R. China （SYS201260）
