解放军医药杂志2015,Vol.27Issue(10):42-46,5.DOI:10.3969/j.issn.2095-140X.2015.10.011
2004—2008年上海市浦东新区居民肺结核病死率相关危险因素分析
Risk Factor Analysis on Fatality Rate of Tuberculosis Patients in Pudong New Area in Shanghai (2004-2008)
摘要
Abstract
Objective To investigate the risk factors of death of tuberculosis ( TB) patients in Pudong New Area in Shanghai. Methods A total of TB 1570 patients diagnosed from January 1, 2004 to December 31, 2008 were recrui-ted in this study, and the effects of age, gender, pathogenesy types, results of first sputum smear, other combined disea-ses and drug resistance on the death induced by TB were analyzed using Kaplan-Meier method, Log-rank test and Cox multivariate regression model. Results The result of single factor analysis showed that male patients more than 60 years old with positive result of first sputum smear, retreatment, delaying diagnosis and treatment, lesions range equal to or more than 3 lung fields, multiple drug resistant pulmonary tuberculosis and other combined diseases were the risk factors of death of TB patients (P<0. 05, P<0. 01). The result of Cox multivariate regression analysis showed that age, gen-der, result of first sputum smear, treatment methods, lesions range and other combined diseases were the risk factors of death of TB patients (P<0. 05). Conclusion Related measures can be given to the male elderly TB patients with posi-tive result of first sputum smear, retreatment, large lesions range and other combined diseases, which may reduce the mortality rate of TB patients.关键词
结核,肺/死亡原因/危险因素/流行病学研究Key words
Tuberculosis/pulmonary/Cause of death/Risk factors/Epidemiologic studies分类
医药卫生引用本文复制引用
张懿行,徐飚,王伟炳,沈鑫,李朋,王沛,李小攀..2004—2008年上海市浦东新区居民肺结核病死率相关危险因素分析[J].解放军医药杂志,2015,27(10):42-46,5.基金项目
国 家 "十 二 五" 科 技 重 大 专 项(2013ZX10004903) (2013ZX10004903)
上海市卫生和计划生育委员会科研课题面上项目(20134128) (20134128)
上海市浦东新区卫生计生委卫生科技项目(PW2013D-12) (PW2013D-12)