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黏红酵母CCZU-G5选择性加氢柠檬醛合成香叶醇

朱劼 汪云 李晨旸 符梦婷 王利群 何玉财

化工进展Issue(5):1122-1126,5.
化工进展Issue(5):1122-1126,5.DOI:10.3969/j.issn.1000-6613.2013.05.027

黏红酵母CCZU-G5选择性加氢柠檬醛合成香叶醇

Selective hydrogenation of citral to geraniol using Rhodotorula mucilaginosa CCZU-G5

朱劼 1汪云 1李晨旸 1符梦婷 1王利群 1何玉财1

作者信息

  • 1. 常州大学制药与生命科学学院,江苏 常州 213164
  • 折叠

摘要

Abstract

Biological conversion of citral to geraniol was studied using Rhodotorula mucilaginosa CCZU-G5 as fermentation strain. The effects of culture time,co-substrate concentration,initial substrate concentration,cell quantity and the reaction time on selective hydrogenation of citral to geraniol were investigated to determine the optimal fermentation conditions. The results showed that after 28 h culturing,yeast cells reached the end of the logarithmic growth phase,in which the quantity and activity of the cells were at a high level. In the process of biological conversion,the optimal fermentation conditions were as follows:glucose concentration 40 g/L,initial citral concentration 4 g/L,yeast cell concentration 0.4 g/mL and reaction time 22 h. Under these conditions,citral conversion and geraniol selectivity reached 88.6% and 95.2%,respectively. The study lays the foundation for commercialized biosynthesis of geraniol.

关键词

黏红酵母/柠檬醛选择性加氢/香叶醇

Key words

Rhodotorula mucilaginosa/selective hydrogenation of citral/geraniol

分类

生物科学

引用本文复制引用

朱劼,汪云,李晨旸,符梦婷,王利群,何玉财..黏红酵母CCZU-G5选择性加氢柠檬醛合成香叶醇[J].化工进展,2013,(5):1122-1126,5.

基金项目

江苏省高校自然科学研究项目(12KJB530001)及常州市生物医药科技专项(CE20115053)。 ()

化工进展

OA北大核心CSCDCSTPCD

1000-6613

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