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H PLC 法测定骨康胶囊中含芍药苷的量

曹明珠 凌雪宇 王家栋 冯伟旭

哈尔滨商业大学学报(自然科学版)Issue(5):533-535,563,4.
哈尔滨商业大学学报(自然科学版)Issue(5):533-535,563,4.

H PLC 法测定骨康胶囊中含芍药苷的量

Determination of paeoniflorin in Gukang capsules by HPLC

曹明珠 1凌雪宇 1王家栋 1冯伟旭1

作者信息

  • 1. 哈药集团世一堂制药厂,哈尔滨150078
  • 折叠

摘要

Abstract

To establish an HPLC method for the determination of paeoniflorin in Gukang cap-sules.The sample was extracted in methanol by ultrasonic .The paeoniflorin content of Gu-kang capsules was determined on C 18 chromatographic column using HPLC .Methanol -wa-ter (28∶72) was used as the mobile phase using .The detection wavelength was 230 nm. The flow rate was 1.0 mL/min.Paeoniflorin linear range was 9.8 ~99.0 μg/mL, and the correlation coefficient r was 0.999 8.And the average recovery rate was 99.46%.The pro-cessing method is reasonable .The methodology conforms to the requirements of the quantita-tive.This method can be used for the determination of paeoniflor in Gukang capsules .

关键词

骨康胶囊/芍药苷/HPLC法

Key words

Gukang capsules/paeoniflorin/HPLC

分类

医药卫生

引用本文复制引用

曹明珠,凌雪宇,王家栋,冯伟旭..H PLC 法测定骨康胶囊中含芍药苷的量[J].哈尔滨商业大学学报(自然科学版),2015,(5):533-535,563,4.

哈尔滨商业大学学报(自然科学版)

1672-0946

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