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阿替普酶静脉溶栓治疗急性脑梗死24例临床分析

许燕平

中国实用神经疾病杂志Issue(20):11-12,2.
中国实用神经疾病杂志Issue(20):11-12,2.

阿替普酶静脉溶栓治疗急性脑梗死24例临床分析

Clinical analysis of 24 cases with acute cerebral in farction treated with alteplaseintravenous thrombolytic ther-apy

许燕平1

作者信息

  • 1. 江苏张家港市第一人民医院神经内科 张家港 215600
  • 折叠

摘要

Abstract

Objective To observe the efficacy and safety of intravenous thrombolysis with alteplase(rt‐PA) in the treat‐ment of acute cerebral infarction .Methods 40 patients with acute cerebral infarction from 2011 to 2014 were divided into the&nbsp;treatment group (24 cases) and the control group (16 cases) .The NIHSS scores were analyzed before thrombolysis and on the 1st and 7th day after thrombolysis ,and mRS scores were evaluated at 3 months after thrombolysis .The major adverse reac‐tions were also observed in this study .Results The NIHSS scores significantly decreased (P<0 .05) on 7th day after throm‐bolysis compared with before thrombolysis in all 24 cases of the treatment group .According to mRS scores ,13 cases (54 .2% ) of the treatment group had good prognosis;while 7 cases (43 .7% ) of the control group had good prognosis .One patient recov‐ered from symptomatic cerebral hemorrhage after thrombolytic therapy .Conclusion In the treatment window ,rt‐PA throm‐bolysis may be an effective and safe therapy for the acute cerebral infarction .

关键词

急性脑梗死/阿替普酶/静脉溶栓

Key words

Acute cerebral infarction/rt-PA/Intravenous thrombolysis

分类

医药卫生

引用本文复制引用

许燕平..阿替普酶静脉溶栓治疗急性脑梗死24例临床分析[J].中国实用神经疾病杂志,2015,(20):11-12,2.

中国实用神经疾病杂志

1673-5110

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