中国实用神经疾病杂志Issue(22)：8-9,10,3.
神经干细胞移植治疗脑梗死的临床观察
Clinical observation of neural stem cells transplantation in the treatment of cerebral infarction
摘要
Abstract
Objective To observe the clinical effect of neural stem cell transplantation in the treatment of cerebral infarc‐tion.Methods 60 cases with cerebral infarction were randomly divided into intravenous injection group (14 cases) ,lumbar puncture (18 cases) and control group (28 cases). Patients in control group were given routine therapy. Besides routine treat‐ment ,the intravenous injection group received neural stem cells infusion by elbow vein injection ;patients in the lumbar punc‐ture group were implanted into neural stem cells through the lumbar puncture. The functional independence scale (FIM ) of the three groups were performed before and after treatment.Results Before treatment ,the FIM scores in the control group ,intra‐venous injection group and lumbar puncture group showed no statistically significant differences (P>0.05);After treatment , compared with control group ,FIM scores in intravenous group and lumbar puncture group revealed statistically significant difference (P<0.05). After treatment ,the difference of FIM scores between intravenous group and lumbar puncture group was a statistical significant (P<0.05).Conclusion Neural stem cells is an effective method in the treatment of cerebral infarc‐tion ,especially the application of subarachnoid cavity injection by lumbar puncture method can significantly improve the prog‐nosis of patients with cerebral infarction and enhance their quality of life.关键词
神经干细胞/移植/脑梗死Key words
Neural stem cells/T ransplantation/Cerebral infarction分类
医药卫生引用本文复制引用
张敏,吴世陶,刘磊,赵源征,石磊,郭亚培,崔明,刘恒方..神经干细胞移植治疗脑梗死的临床观察[J].中国实用神经疾病杂志,2015,(22):8-9,10,3.基金项目
河南省教育厅科学技术研究重点项目 （）
