湖南中医药大学学报2015，Vol.35Issue(9)：65-69,5.DOI:10.3969/j.issn.1674-070X.2015.09.019
抗苗勒氏管激素与多囊卵巢综合征卵泡发育相关性的研究进展
Research Progress of the Correlation of anti-Müllerian Hormone and PCOS Follicular Development
摘要
Abstract
Follicular dysplasia is one of the core pathophysiological mechanisms of polycystic ovary syndrome(PCOS). The role of ovarian local regulation of follicle development has been increasingly prominent. Anti-müllerian hormone (AMH) is the negative feedback regulation mechanism of follicle development and closely associated with female ovarian function. The important impact factors of PCOS follicular dysplasia and sex hormone synthesis disorder may be that abnormal AMH expression in patients with PCOS. AMH can predict early PCOS, diagnose the degree of PCOS follicular developmental disorder as specific indicator, and has become one of novel targets and the breakthrough points in the diagnosis and treatment of PCOS. Therefore, it is necessary to target ovarian local AMH for further study of the problems like its produce time, cellular localization and molecular mechanism.关键词
抗苗勒氏管激素/多囊卵巢综合征/卵泡发育Key words
anti-müllerian hormone/polycystic ovary syndrome/follicular development分类
医药卫生引用本文复制引用
杨硕,尤昭玲,孙晓峰,李靖,林星辉..抗苗勒氏管激素与多囊卵巢综合征卵泡发育相关性的研究进展[J].湖南中医药大学学报,2015,35(9):65-69,5.基金项目
国家自然科学基金资助项目 (81503611), 湖南省自然科学基金资助项目 (2015JJ6078), 湖南省教育厅科学研究基金资助项目(15B180). （81503611）
