湖南中医药大学学报Issue(11):70-72,3.DOI:10.3969/j.issn.1674-070X.2015.11.019
COX-2/Nrf2信号通路在防治前列腺增生症中的研究进展
Research Progress of COX-2/Nrf2 Signaling Pathway in Prevention and Treatment of Benign Prostatic Hyperplasia
摘要
Abstract
〔Abstract〕 Benign prostatic hyperplasia (BPH) is the most important diseases of urinary system in middle-aged males, and its main clinical manifestations is urinary tract symptoms, which has serious impact on life quality of patients. In recent years, the effects of anti-inflammatory and anti-oxidative stress of COX-2/Nrf2 signaling pathway were demonstrated. The cell biological mechanisms of inflammation and oxidative stress in the development of BPH has been elucidated. Based on the COX-2/Nrf2 signal pathway, the research of Chinese medicine prevention and treatment of BPH get the attention of us. This paper elaborates the progress of COX-2/Nrf2 signaling pathway in the prevention and treatment of BPH.关键词
前列腺增生症/COX-2/Nrf2/抗炎/抗氧化Key words
prostatic hyperplasia/COX-2/Nrf2/anti-inflammatory/antioxidant分类
医药卫生引用本文复制引用
全丹妮,颜苗,樊新荣,邓阳,胡乔铭,刘文琛..COX-2/Nrf2信号通路在防治前列腺增生症中的研究进展[J].湖南中医药大学学报,2015,(11):70-72,3.基金项目
国家自然科学基金(81373708,81202985)。 ()