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护心康对动脉粥样硬化兔TLR4mRNA的干预作用

屈波 蔡光先 董晓斐 刘柏炎 刘红萍

中医药导报Issue(2):88-89,2.
中医药导报Issue(2):88-89,2.

护心康对动脉粥样硬化兔TLR4mRNA的干预作用

Intervention Effect of Huxinkang on TLR4mRNA in Atherosclerosis Rabbits

屈波 1蔡光先 1董晓斐 1刘柏炎 1刘红萍1

作者信息

  • 1. 湖南中医药大学,湖南 长沙 410007
  • 折叠

摘要

Abstract

Objective: To explore the mechanism of Huxinkang on atherosclerosis rabbit . Methods:Atherosclerosis rabbits were induced by high lipid diet. The rabbits were divided into Huxinkang low, middle and high dose groups. The samples of aorta were taken for TLR4mRNA in the AS plaque. Results: The expression of TLR4mRNA in AS plaque were all increased obviously in the Huxinkang low, middle and high dose groups. The high dose group is better than low dose group (P<0.05) . Conclusion: Huxinkang can decrease TLR4mRNA in plaque.

关键词

护心康/动脉粥样硬化//TLR4mRNA/丹参/瓜蒌

Key words

Huxinkang/Atherosclerosis/Rabbit/TLR4mRNA/Salvia/Trichosanthes

分类

医药卫生

引用本文复制引用

屈波,蔡光先,董晓斐,刘柏炎,刘红萍..护心康对动脉粥样硬化兔TLR4mRNA的干预作用[J].中医药导报,2013,(2):88-89,2.

基金项目

湖南省中医药科研计划项目(2009023) (2009023)

湖南省教育厅科学研究项目(09B07) (09B07)

湖南省自然科学基金项目(10JJ3054) (10JJ3054)

中医药导报

OACSTPCD

1672-951X

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