中医药导报Issue(5)：89-90,91,3.
枸杞多糖对小鼠移植性肝癌抑制作用的实验研究
Experimental Study on inhibitory effects of Lycium Barbarum Polysaccharide in Hepatoma-xenograft Mice
刘静1
作者信息
- 1. 陕西学前师范学院，陕西 西安 710100
- 折叠
摘要
Abstract
Objective: To study the inhibitory effects of Lycium Barbarum Polysaccharide (LBP) in hepatoma-xenograft mice. Methods: 48 mice were randomly divided into the LBP high-dose group (20 mg/kg), middle dose group (10 mg/kg), low-dose group (5 mg/kg), cyclophosphamide group (20 mg/kg), control group and model group, to study the effect on mortality in hepatoma-xenograft mice, tumor volume, and tumor necrosis by LBP. Results: Compared with the model group, TNF-α secre-tion in the LBP different dose groups were significantly increased (P<0.05), and tumor volume in the LBP different dose groups was significantly reduced (P<0.05); Tumor volume in cyclophosphamide group has also significantly reduced; the differ-ence on inhibition of tumor growth between the LBP high dose group and cyclophosphamide group was not statistically signifi-cant (P>0.05). Conclusion: LBP can enhance immune function, inhibit tumor cells and has a significant inhibitory effect on hepatoma-xenograft mice.关键词
枸杞多糖/移植性肝癌/免疫能力Key words
LBP/Hepatoma-xenograft/Immunity分类
医药卫生引用本文复制引用
刘静..枸杞多糖对小鼠移植性肝癌抑制作用的实验研究[J].中医药导报,2013,(5):89-90,91,3.
