摘要
Abstract
Objective: To establish the method to determine the content of Notoginsenoside R 1, Ginsenoside Rb1 and Gin-senoside Rg1 in Compound Danshen Tablets by HPLC. Methods: The HPLC method was applied and Diamonsil C 18(250 mm×4.6 mm, 5μm) was used; the ACN-H3PO4 (0.05%) was used as mobile phase; detective wave was 203 nm; flow rate was 10 mL/min. Results:The regression equations of notoginsenoside R1 was Y=187.0X+16.16, r=0.9997, and the linear range of notoginseno-side R1 was 0.366-3.206μg; the linear range of ginsenoside Rb1 was 0.911-9.241μg; the regression equations of ginsenoside Rg1, was Y=403.6X+9.113, r=0.9994,and the linear range of ginsenoside Rg1 was0.841-8.431 μg. Conclusion: The HPLC is promise method to determine the content of Notoginsenoside R1, Ginsenoside Rb1 and Ginsenoside Rg1, which is benefit to con-trol the quality of Compound Danshen Tablets.关键词
三七皂苷R1/人参皂苷Rb1/人参皂苷Rg1/复方丹参片Key words
Notoginsenoside R1/Ginsenoside Rb1/Ginsenoside Rg1/Compound Danshen Tablets分类
医药卫生
