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滋肾活血汤对2型糖尿病大鼠血管病变及肾脏保护的研究*

颜国富 李淑君 胡仙 杜亮亮

中医药导报Issue(8):77-79,3.
中医药导报Issue(8):77-79,3.

滋肾活血汤对2型糖尿病大鼠血管病变及肾脏保护的研究*

Protection of Kidney-Enrichment And Blood-Quickening Decoction on Vasculopathy and Kidney in Type 2 Diabetic Rats

颜国富 1李淑君 1胡仙 1杜亮亮1

作者信息

  • 1. 岳阳市中医院,湖南 岳阳 414000
  • 折叠

摘要

Abstract

Objective: To explore the effect of Kidney-Enrichment And Blood-Quickening Decoction on blood sugar, fast-ing insulin, blood fat, renal function, and the vasculitis index of ET, NO, INS and TNF-α. Methods: 42 female Wister rats were divided into model control group, Chinese medicine group, melbine group, Chinese medicine-melbine group and blank control group. After intragastric administration of 8 weeks, the biochemical indicator, vasculitis index and renal function were tested. Results: Kidney-Enrichment And Blood-Quickening Decoction can reduce the serum NO, INS, TNF-α, TG, BUN, CREA and UA in Type 2 diabetic rats. Conclusion: Kidney-Enrichment And Blood-Quickening Decoction can relieve the vas-cular inflammation, with protective function on kidney. And the function was more obvious with low dosage of melbine in ear-ly stage.

关键词

滋肾活血汤/2型糖尿病大鼠/血管病变/肾功能

Key words

Kidney-Enrichment And Blood-Quickening Decoction/Type 2 diabetic rats/Vasculopathy/Renal function

分类

医药卫生

引用本文复制引用

颜国富,李淑君,胡仙,杜亮亮..滋肾活血汤对2型糖尿病大鼠血管病变及肾脏保护的研究*[J].中医药导报,2013,(8):77-79,3.

基金项目

岳阳市科技局资助课题 ()

中医药导报

OACSTPCD

1672-951X

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