中医药导报Issue(8):77-79,3.
滋肾活血汤对2型糖尿病大鼠血管病变及肾脏保护的研究*
Protection of Kidney-Enrichment And Blood-Quickening Decoction on Vasculopathy and Kidney in Type 2 Diabetic Rats
摘要
Abstract
Objective: To explore the effect of Kidney-Enrichment And Blood-Quickening Decoction on blood sugar, fast-ing insulin, blood fat, renal function, and the vasculitis index of ET, NO, INS and TNF-α. Methods: 42 female Wister rats were divided into model control group, Chinese medicine group, melbine group, Chinese medicine-melbine group and blank control group. After intragastric administration of 8 weeks, the biochemical indicator, vasculitis index and renal function were tested. Results: Kidney-Enrichment And Blood-Quickening Decoction can reduce the serum NO, INS, TNF-α, TG, BUN, CREA and UA in Type 2 diabetic rats. Conclusion: Kidney-Enrichment And Blood-Quickening Decoction can relieve the vas-cular inflammation, with protective function on kidney. And the function was more obvious with low dosage of melbine in ear-ly stage.关键词
滋肾活血汤/2型糖尿病大鼠/血管病变/肾功能Key words
Kidney-Enrichment And Blood-Quickening Decoction/Type 2 diabetic rats/Vasculopathy/Renal function分类
医药卫生引用本文复制引用
颜国富,李淑君,胡仙,杜亮亮..滋肾活血汤对2型糖尿病大鼠血管病变及肾脏保护的研究*[J].中医药导报,2013,(8):77-79,3.基金项目
岳阳市科技局资助课题 ()