基础医学与临床Issue(1)：117-121,5.
NLRP3炎性小体研究进展
Research advances in NLRP3 inflammasome
摘要
Abstract
Inflammasomes are multiprotein complexes that can recognize pathogenic microorganisms and stress -asso-ciated endogenous molecules and play an important role in innate immune system .Inflammasomes cause inflamma-tion response by inducing maturation of inflammatory cytokines interleukin ( IL)-1βand IL-18 through activation of caspase-1 ,and involve in the pathogenesis of various diseases such as cryopyrin-associated periodic syndrome , is-chemia-reperfusion injury and atherosclerosis .关键词
炎性小体/NLRP3/IL-1βKey words
inflammasome/NLRP3/IL-1β分类
医药卫生引用本文复制引用
魏祺,程晓曙..NLRP3炎性小体研究进展[J].基础医学与临床,2015,(1):117-121,5.基金项目
国家“十二五”科技支撑计划 （）
