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黑龙江省健康青少年血清钙、磷、碱性磷酸酶的参考范围

程歆琦 程倩 邱玲 刘荔 刘茜 韩少梅 朱广瑾

基础医学与临床Issue(9):1205-1208,4.
基础医学与临床Issue(9):1205-1208,4.

黑龙江省健康青少年血清钙、磷、碱性磷酸酶的参考范围

Reference intervals of serum calcium, phosphate and alkaline phosphatase of healthy school children and adolescents in Heilongjiang province

程歆琦 1程倩 1邱玲 1刘荔 1刘茜 1韩少梅 2朱广瑾3

作者信息

  • 1. 中国医学科学院北京协和医学院北京协和医院检验科,北京100730
  • 2. 中国医学科学院基础医学研究所流行病统计学系,北京100005
  • 3. 生理学与病理生理学系,北京100005
  • 折叠

摘要

Abstract

Objective To analyze the serum calcium , phosphate and alkaline phosphatase level among apparently healthy school children and adolescents in Heilongjiang Province and establish the reference intervals in different gender and different age groups .Methods Random sample of 2 101 primary and secondary school students from 9 to 18-year-old was collected from different district of Heilongjiang Province including Harbin and Mudanjiang from July 2008 to June 2009 .The fasting venous blood was collected and serum calcium , phosphate and alkaline phos-phatase concentration was measured as soon as possible .After screening outlier individual , a total of 2 091 subjects were enrolled.The reference intervals of serum calcium , phosphate and alkaline phosphatase for healthy school children and adolescents were established by gender and age ( P2.5 to P97.5 ) .Results The change tendency of serum calcium, phosphate and alkaline phosphatase with age and sex were presented .All these parameters had&nbsp;shown inverse relationship with age and were significantly higher in boys than girls (P<0.001).Serum calcium, phosphate of both sexes and serum alkaline phosphatase of girls declined progressively with age .However , the highest alkaline phosphatase level was seen at 13 years in boys.Alkaline phosphatase showed a positive correlation with age before 13 years of age , but after that alkaline phosphatase started to decline .Conclusions Reference in-tervals of serum calcium , phosphate and alkaline phosphatase for healthy school children and adolescents in Hei -longjiang Province in the age group of 9-18 years were presented , which supply good reference value for clinicians especially pediatricians to interpret the results of school children and adolescents and make decision .

关键词

健康青少年///碱性磷酸酶/参考范围

Key words

healthy school children and adolescents/calcium/phosphate/alkaline phosphatase/reference interval

分类

医药卫生

引用本文复制引用

程歆琦,程倩,邱玲,刘荔,刘茜,韩少梅,朱广瑾..黑龙江省健康青少年血清钙、磷、碱性磷酸酶的参考范围[J].基础医学与临床,2015,(9):1205-1208,4.

基金项目

科技部科技基础性工作专项 ()

基础医学与临床

OACSCDCSTPCD

1001-6325

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