基础医学与临床Issue(10)：1414-1418,5.
抑癌基因PTEN非基因调控的研究进展
Advances in the non-genetic regulation of PTEN tumour suppressor activity
尹博炜 1张谢 2李宏2
作者信息
- 1. 宁波大学医学院，浙江宁波315211
- 2. 宁波市医疗中心李惠利医院，浙江宁波315040
- 折叠
摘要
Abstract
Mutations and deletions of the tumour suppressor PTEN are frequently involved in the development of cancer.However, PTEN is also tightly controlled by various non-genomic mechanisms,such as the epigenetic silen-cing of PTEN, post-transcriptional regulation by non-coding RNAs and post-translational modification.关键词
PTEN/肿瘤抑制因子/PI3K/AKT信号通路/肿瘤Key words
PTEN/tumour suppressor/PI3K-Akt/PKB pathway/cancer分类
医药卫生引用本文复制引用
尹博炜,张谢,李宏..抑癌基因PTEN非基因调控的研究进展[J].基础医学与临床,2015,(10):1414-1418,5.
