井冈山大学学报（自然科学版）Issue(1)：95-101,7.DOI:10.3969/j.issn.1674-8085.2013.01.021
C-met和COX-2在非小细胞肺癌中的表达与临床意义
EXPRESSION AND CLINICAL SIGNIFICANCE OF C-MET AND COX-2 IN NON-SMALL CELL LUNG CANCER
王风婷1
作者信息
- 1. 井冈山大学临床医学院，江西，吉安 343000
- 折叠
摘要
Abstract
Objective: To discuss the expressions and clinical significance of C-met and COX-2 in NSCLC. Methods:60 samples of NSCLC tissue and 20 samples of normal lung tissue were selected from January in 2010 to June in 2011. The expressions of C-met and COX-2 in NSCLC and normal lung tissue were detected by immunohistochemical method. Results:C-met and COX-2 expression in NSCLSC were significantly higher than that in peri-cancer normal lung tissue. The over-expression of C-met and COX-2 in NSCLC was close correlative with pathological types, metastasis, TNM stage;The correlation for expression of C-met and COX-2 in NSCLC was positive. Conclusion:C-met and COX-2 play a very important role in the occurrence and progress of NSCLC. C-met and COX-2 may become biomarker of early diagnosis and prognostic evaluation. The significant correlation between them shows their interaction in NSCLC happen and development, which provides experimental data for exploring a new method of the therapy of NSCLC.关键词
C-met/COX-2/非小细胞肺癌/免疫组织化学Key words
C-met/COX-2/Non-Small Cell Lung Cancer (NSCLC)/immunohistochemistry分类
医药卫生引用本文复制引用
王风婷..C-met和COX-2在非小细胞肺癌中的表达与临床意义[J].井冈山大学学报（自然科学版）,2013,(1):95-101,7.
