摘要
Abstract
Objective To investigate the use of antibiotics in the treatment of patients with acute upper respiratory tract infection. Methods From January 2012 to December 2014,prescriptions for acute upper respiratory tract infection in outpatient clinic were retrospectively and among them,prescriptions with use of antibiotics were randomly selected.The use of antibiotics was analyzed. Results There were 63 694 prescriptions on treating acute upper respiratory tract infec-tion from January 2012 to December 2014 in clinic in the investigation.Among them,9997 prescriptions with use of an-tibiotics were selected accounting for 15.70%.With regard to medication reasonability,the number of rationality,basic rationality,and irrationality was 2765 cases (27.66%),5005 cases (50.06%),and 2227 cases (22.28%) respectively.Among 2227 irrational use of antibiotics,overdose stipulated by specification in 164 prescriptions (7.36%),usage and dosage be-ing inconsistent with specification in 248 prescriptions (11.14%),inappropriate frequency of administration in 206 pre-scriptions (9.25%),single overdose in 305 prescriptions (13.70%),repeated administration 92 prescriptions (4.13%),un-defined diagnosis in 333 prescriptions (14.95%),no indication of application in 524 prescriptions (23.53%),excessive drugs in 99 prescriptions (4.45%),inappropriate administration route in 121 prescriptions (5.43%),off-label drug use 42 prescriptions (1.86%),drug interactions in 6 prescriptions (0.27%),lack of dose in 83 prescriptions (3.73%),and con-traindication in 4 prescriptions (0.18%).The number of use of two kinds of antibiotics was greatly less than that by sin-gle antibiotic with a statistical difference (P<0.01).The number of prescriptions in antibiotics combining with antiviral drugs was much higher than that by antibiotics combining with corticosteroids,which displayed a statistical difference (P<0.01). Conclusion There is still antibiotics abused in the treatment of acute upper respiratory tract infection in out-patient clinics,and standardized management needs to be strengthened.关键词
急性上呼吸道感染/合理使用/抗生素/处方Key words
Acute upper respiratory tract infection/Rational use/Antibiotics/Prescription分类
医药卫生
