中国当代医药Issue(29)：21-25,5.
三氧化二砷诱导线粒体途径细胞凋亡机制的研究进展
Research progress of Arsenic trioxide induces mitochondrial pathway apoptosis mechanism
李丹 1宋婷婷 1刘伟华 1谢坤霞 1王晶晶 1肖延风1
作者信息
- 1. 西安交通大学第二附属医院儿科，西安 710004
- 折叠
摘要
Abstract
By inducing cell apoptosis,Arsenic trioxide (ATO) plays a role of anti-tumor.In recent years,the relationship between ATO and mitochondrial apoptosis signaling pathways is becoming a hot research spot.A large number of stud-ies of scholars both at home and abroad have shown that ATO involved in mitochondrial pathway and induced each link of apoptosis.The study of these mechanisms provide a wider range of ideas for us to choose ATO sensitization agent,are helpful to reduce the ATO dose to reduce cytotoxicity effect and have important clinical significance for new drug research and development.关键词
三氧化二砷/细胞凋亡/线粒体途径Key words
Arsenic trioxide/Apoptosis/Mitochondrial pathway分类
医药卫生引用本文复制引用
李丹,宋婷婷,刘伟华,谢坤霞,王晶晶,肖延风..三氧化二砷诱导线粒体途径细胞凋亡机制的研究进展[J].中国当代医药,2015,(29):21-25,5.
