中国当代医药Issue(29):48-50,54,4.
动态血糖监测系统联合胰岛素泵持续皮下输注胰岛素治疗难治性糖尿病的效果及安全性研究
Effect and safety study of continuous glucose monitoring system combined with continuous subcutaneous insulin infusion in the treatment of refrac-tory diabetes
杨柳 1张小东 1陈岚 1曹燕 1严红琴1
作者信息
- 1. 江苏省靖江市人民医院内分泌科,江苏靖江 214500
- 折叠
摘要
Abstract
Objective To explore the efficacy and safety of continuous glucose monitoring system (CGMS) combined with continuous subcutaneous insulin infusion (CSII) in the treatment of refractory diabetes. Methods 40 patients with re-fractory diabetes in our hospital from October 2012 to November 2014 were selected and randomly divided into the ob-servation group and the control group,with 20 patients in each group.The observation group was treated with CGMS combined with CSII,the control group was given multiple daily injection of insulin (MDI).The effect and safety in two groups was compared. Results The total effective treatment rate in the observation group was 95.0%,which was higher than 80.0%in the control group,with significant difference (P<0.05).The amount of insulin,the frequency of hypoglycemia and the fluctuation of blood glucose in the observation group was less than that in the control group,with significant differ-ence (P<0.05).The standard time of blood glucose in the observation group was shorter than that in the control group, with significant difference (P<0.05).The level of blood glucose after treatment in the observation group was lower than that in the control group,with significant difference (P<0.05). Conclusion For the patients with refractory diabetes,CGMS com-bined with CSII has better safety and effectiveness than MDI,it is worthy of promotion and application.关键词
动态血糖监测系统/胰岛素泵持续皮下输注/难治性糖尿病/疗效/安全性Key words
Continuous glucose monitoring system/Continuous subcutaneous insulin infusion/Refractory diabetes/Effi-cacy/Safety分类
医药卫生引用本文复制引用
杨柳,张小东,陈岚,曹燕,严红琴..动态血糖监测系统联合胰岛素泵持续皮下输注胰岛素治疗难治性糖尿病的效果及安全性研究[J].中国当代医药,2015,(29):48-50,54,4.