全科护理Issue(27):2671-2674,4.DOI:10.3969/j.issn.1674-4748.2015.27.003
自体干细胞移植治疗晚期肝硬化病人的疗效及围术期护理
Curative effect and perioperative care of advanced cirrhosis patients treated with autologous stem cells transplanta-tion
刘凤 1姚豫桐 1李福宣1
作者信息
- 1. 610072,四川省医学科学院·四川省人民医院
- 折叠
摘要
Abstract
Objective:To summarize the curative effect and perioperative care of advanced cirrhosis patients trea-ted with autologous stem cells transplantation.Methods:A total of 100 advanced cirrhosis patients who had fail-ure conservative therapy by internal medicine were conducted with autologous peripheral blood stem cells trans-plantation for advanced cirrhosis.Preoperative targeted psychological intervention,targeted psychological inter-vention was taken for them,and postoperative rehabilitation guidance was did well,the drug adverse reactions were observed,the vital signs were observed closely and to prevent the complications.Results:One year surviv-al rate was 100% in 100 patients ,the ascites was gradually reduced and disappeared in 52 patients with massive ascites.4 patients underwent upper gastrointestinal bleeding at postoperative 3 months and 3 patients developed with Ⅰ Ⅱ degree of hepatic encephalopathy.After transplantation,the liver synthetic function,liver reserve function and liver elasticity determination were significantly improved (P <0.05 )compared with that before transplantation.Conclusion:Autologous peripheral blood stem cells transplantation could improve the liver func-tion and liver tissue morphology of advanced cirrhosis patients and their quality of life.Perioperative holistic nursing can promote the rehabilitation of patients and improve the curative effect.关键词
晚期肝硬化/自体外周血干细胞移植/肝功能/围术期护理Key words
advanced cirrhosis/autologous peripheral blood stem cells/liver function/nursing分类
医药卫生引用本文复制引用
刘凤,姚豫桐,李福宣..自体干细胞移植治疗晚期肝硬化病人的疗效及围术期护理[J].全科护理,2015,(27):2671-2674,4.