江西农业大学学报2015，Vol.37Issue(5)：894-897,4.DOI:10.13836/j.jjau.2015135
多西环素在肉鸡可食性组织中的残留研究
A Study on the Residues of Doxycycline in the Broiler Edible Tissues
摘要
Abstract
To study the residues of the therapeutic dose of doxycycline in broiler edible tissues,doxycyc-line was given at the concentrations of 100 mg/L(group 1) and 100 mg/kg(group 2) ,which was mixed in the drinking water and feed,samples of chicken' s live,kidney,muscle,skin-fat were taken at different times to measure their residue levels by means of the high performance liquid chromatography.The result showed as fol-lows,during administration,the concentration of doxycycline in the broiler tissue was gradually accumulated as time on,and reached the peak at the 4th or 5th days after the administration.Compared group 1 with group 2,the former' s concentration of the medicine was significantly (P<0.05) or very significantly higher (P<0.01) than that of the latter.In the days after the first withdrawal,the doxycycline concentration of the medicine in each tissue declined rapidly,and then eliminated slowly.In the days after the 14th withdrawal,the doxycycline con-centration in liver,kidney,muscle,skin and fat in group 1 and group 2 were below the maximum residue limitsprescribed by the Ministry of Agriculture.For the safe reason,when the doxycycline was given at 100 mg/L through the drinking water and 100 mg/kg through the feed,the withdrawal period should be 28 days.关键词
多西环素/肉鸡/残留/高效液相色谱法Key words
doxycycline/chickens/residues/high performance liquid chromatography分类
农业科技引用本文复制引用
刘明生,甘辉群,胡国良,陆广富,傅师一,万文根,贺生中..多西环素在肉鸡可食性组织中的残留研究[J].江西农业大学学报,2015,37(5):894-897,4.基金项目
江苏省农业三新工程项目(SXGC[2013]291)和江苏农牧科技职业学院自然科学科研项目(NSFZN1401) （SXGC[2013]291）
